Challenges of denosumab in giant cell tumor of bone, and other giant cell-rich tumors of bone
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چکیده
منابع مشابه
Giant cell tumor of the sphenoid bone
Background: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. Giant cell tumor (GCT) of the sphenoid bone is relatively rare. In this report, we describe a tumor of the greater wing of left sphenoid bone. Case presentation: A 31-year-old female was presented with headache, proptosis and diplopia of her left eye. Cranial magnetic resonance ima...
متن کاملGiant Cell Tumor of Bone - an Overview
Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal ...
متن کاملgiant cell tumor of bone - an overview
giant cell tumors (gct) are benign tumors with potential for aggressive behavior and capacity to metastasize. although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. its histogenesis remains unclear. it is characterized by a proliferation of mononuclear stromal ce...
متن کاملgiant cell tumor of the sphenoid bone
background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...
متن کاملA Recurrent Giant Cell Tumor of Bone Treated with Denosumab
Although the giant cell tumor of bone is generally classified as a benign tumor it can rarely metastasize and has a potential risk of local recurrence. We want to report about a female patient who suffered from a recurrence of a giant cell tumor of bone after the implantation of a total endoprosthesis of the knee joint. We have treated her with denosumab, which is a receptor activator of nuclea...
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ژورنال
عنوان ژورنال: Current Opinion in Oncology
سال: 2019
ISSN: 1040-8746,1531-703X
DOI: 10.1097/cco.0000000000000529